ICSI (Intra-Cytoplasmic Sperm Injection)
A highly advanced fertilization technique used to overcome severe male infertility and improve IVF success.

Overview & Clinical Approach
A single healthy sperm is directly injected into an egg to achieve fertilization.
ICSI (Intra-Cytoplasmic Sperm Injection) is an advanced ART (Assisted Reproductive Technology) procedure, primarily used for severe male infertility. Unlike standard IVF - where eggs and sperms are mixed together - ICSI requires only one good sperm, which is manually injected into the egg by an embryologist.
This bypasses sperm motility and morphology problems and increases the chances of successful fertilization.
Maa Nursing Home and NetraJyoti Eyecare Centre is equipped with specialized micromanipulation technology and expert embryologists to perform ICSI with high accuracy.
Common Symptoms
- Very low or zero sperm count (azoospermia)
- Poor sperm motility or abnormal sperm morphology
- Egg penetration issues
- Failed fertilization in previous standard IVF cycles
- High anti-sperm antibodies or severe female endometriosis
Primary Causes & Risk Factors
- Severe male factor infertility (Oligo-astheno-teratozoospermia)
- Ejaculatory dysfunction or obstructive/non-obstructive azoospermia
Diagnostic Procedures
- Detailed male and female fertility evaluation, semen CASA testing, and ovarian reserve assessment
Treatment Steps
Ovarian Stimulation & Egg Retrieval
Injections stimulate ovaries to produce eggs, retrieved under ultrasound guidance.
Sperm Selection & Micro-Injection (ICSI)
High-magnification micromanipulation selects single motile sperm injected directly into mature egg.
Embryo Culture & Transfer
Embryos cultured 2–5 days and high-quality embryos transferred into uterus.
Are There Any Risks?
- Children born through ICSI and IVF are generally healthy.
- ICSI may slightly increase the chance of passing on certain genetic conditions, usually linked to the underlying infertility in the parents rather than the procedure itself.
Key Treatment Benefits
- Ideal solution for severe male infertility requiring only one healthy sperm cell per egg
- Significantly higher fertilization rates and overcomes past standard IVF failures
- Performed in high-tech micromanipulation labs led by expert embryologists
Consultation for ICSI (Intra-Cytoplasmic Sperm Injection)
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